Table 1.

Clinical characteristics of all uveal melanoma patients (n = 90; univariate analysis) and in vivo tumor take rate (%)

Patients and tumor characteristicsPatients (n)Tumor take rate (%)P
Gender
    Male4723.4NS
    Female4332.6
Age at diagnosis (y)
    <604850.7NS
    ≥604249.2
History of previous cancer
    No8625.6NS (0.06)
    Yes475.0
Primary tumor location
    Anterior to equator30
    On equator7530.7NS
    Posterior to equator1118.2
Origin of tumor sample
    Primary tumor7321.90.02
    Metastatic tumor1752.9
Primary tumor diameter (NA = 4)
    ≤15 mm1816.7NS
    15-18 mm2737.0
    >18 mm4126.8
Primary tumor thickness
    ≤7 mm1729.4NS
    7-10 mm1442.8
    >10 mm5923.7
Retinal detachment (NA = 2)
    No3138.7NS (0.07)
    Yes571.0
Extrascleral invasion (NA = 5)
    No7826.9NS
    Yes728.6
Primary tumor treatment
    No enucleation1735.3NS
    Enucleation7326.1
Histology (n = 73)
    Epithelioid2931.0
    Spindle1936.8NS
    Mixed2313.0
Ciliary body involvement (NA = 1)
    No5322.6NS
    Yes1936.8
Extrascleral involvement (NA = 1)
    No6627.3NS
    Yes616.7
Mitotic index (NA = 9)
    Nil-low7224.2NS
    Medium-high742.8
Monosomy 3 of primary tumors (NA = 10)
    No3020.0NS
    Yes3333.3
Initial treatment
    Proton therapy7335.3NS
    Enucleation1726.1
  • Abbreviations: NA, not available; NS, not significant.