Description of the genes selected in each of the three steps of the first phase
| Selected differentially expressed genes (P < 0.05) | Other selected genes | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Diagnostic and prognostic genes | Diagnostic genes | Prognostic genes | Outliers/Bibliography | Endogenous controls | |||||||||
| n | n overexpressed | n underexpressed | n | n overexpressed | n underexpressed | n | n overexpressed | n underexpressed | |||||
| Affymetrix→ | 216 | Diagnostic | 88 | 128 | 66 | 16 | 50 | 63 | 41 | 22 | 29 | 7 + 3 | 384 |
| TA 384 | Prognostic | 191 | 25 | ||||||||||
| TA 384→ | 25 | Diagnostic | 23 | 2 | 48 | 31 | 17 | 9 | 5 | 4 | 11 | 3 | 96 |
| TA 96 | Prognostic | 21 | 4 | ||||||||||
| TA 96→ | 14 | Diagnostic | 12 | 2 | 20 | 18 | 2 | 5 | 4 | 1 | 6 | 3 | 48 |
| TA 48 | Prognostic | 11 | 3 | ||||||||||
NOTE: Genes are over- or under-expressed in tumor or HG samples with respect to control or LG tumors, respectively. Diagnostic genes: differentially expressed genes between tumor and control samples. Prognostic genes: differentially expressed genes between LG and HG tumor samples (those genes that predict tumor aggressiveness). Genes could be differentially expressed either for diagnosis only or for prognosis only, or for both.