Table 3.

Diagnostic performance of the 12-gene set model in different sets of samples

Gene set model from:Phase IPhase IPhase II
Samples from:Phase IPhase IIPhase II
Overall
    n tumors/n controls244/12197/11497/114
    SN987089
    SP999695
    PPV1009393
    NPV957991
Low-risk NMIBC (Ta or T1 LG without associated CIS)
    n tumors/n controls110/12144/11444/114
    SN965780
    SP999695
    PPV998385
    NPV978592
High-risk NMIBC (Ta or T1 LG with associated CIS, Ta or T1 HG, Tis)
    n tumors/n controls92/12127/11427/114
    SN1008193
    SP999695
    PPV998181
    NPV1009698
MIBC (T2, T3, T4 HG, with or without associated CIS)
    n tumors/n controls42/12126/11426/114
    SN9581100
    SP999695
    PPV988181
    NPV9896100

Abbreviations: PPV, positive predictive value; NPV, negative predictive value.