Table 1.

CTC detection in relation to patient characteristics

Clinical variable at baselineTotal no. of patients analyzed, N = 287 (%)No. of patients with ≥1 CTC/7.5 mL (%)*PNo. of patients with ≥2 CTC/7.5 mL (%)*P
Age (y)
    <50146 (50.9)31 (21.2)0.4712 (8.2)0.152
    ≥50141 (49.1)35 (24.8)19 (13.5)
cT
    T19 (3.1)1 (11.1)0.84900.54
    T2187 (65.2)44 (23.5)21 (11.2)
    T350 (17.4)12 (24)4 (8)
    T441 (14.3)9 (22)6 (14.6)
cN
    N0127 (44.3)34 (26.8)0.22615 (11.8)0.239
    N1143 (49.8)26 (18.2)12 (8.4)
    N214 (4.9)5 (35.7)3 (21.4)
    N33 (1)1 (33.3)1 (33.3)
Histology
    Ductal233 (81.2)56 (24)0.46227 (11.6)0.404
    Lobular25 (8.7)6 (24)3 (12)
    Others29 (10.1)4 (13.8)1 (3.4)
Grading
    G13 (1)00.19700.728
    G2174 (60.6)36 (20.7)18 (10.3)
    G397 (33.8)28 (28.9)12 (12.4)
    No data13 (4.5)2 (15.4)1 (7.7)
HER2
    Negative182 (63.4)41 (22.5)0.80421 (11.5)0.596
    Positive105 (36.7)25 (23.8)10 (9.5)
ER
    Negative123 (42.9)34 (27.6)0.10516 (13)0.297
    Positive164 (57.1)32 (19.5)15 (9.1)
PR
    Negative131 (45.6)36 (27.5)0.09820 (15.3)0.026
    Positive156 (54.4)30 (19.2)11 (7.1)
Triple negativity
    Yes59 (20.6)18 (30.5)0.1249 (15.3)0.216
    No228 (79.4)48 (21.1)22 (9.6)
  • *CTC positivity before and/or after NT.