Table 4.

Peptide-specific T-cell responses

Patient IDPeptides
P1P2P3P6P7P8P4P5P9P13P14P15Totalb
Imm-01-001+++++++++9
Imm-01-002+++++++++++11
Imm-01-0030
Imm-01-004++++++++8
Imm-01-0050
Imm-01-006++++++++++++12
Imm-01-0070
Imm-01-008++++++++++10
Imm-02-001++++4
Imm-02-0020
Imm-02-0030
Imm-02-004+++++++++9
Imm-02-005++++++++++++12
Imm-02-006++++++++++++12
Imm-02-007NDNDNDNDNDNDNDNDNDNDNDNDND
Totala 887678688786

NOTE: Imm-01 (ovarian cancer); Imm-02 (breast cancer).

Positive response is defined as response to specific peptide greater than 40 spots (out of 106 PBMC) over prevaccination and/or negative control response by ELISpot.

ND: Pt Imm-02-007 received only 3 immunizations and did not return for follow-up testing.

  • aTotal number of patients experiencing response to the particular peptide.

  • bTotal number of peptides to which the patient responded.