Table 1.

Summary of overall survival results for 3 phase III randomized trials

Overall survivalStudy D99902BStudy D9901Study D9902A
Sipuleucel-TPlaceboSipuleucel-TPlaceboSipuleucel-TPlacebo
(n = 341)(n = 171)(n = 82)(n = 45)(n = 65)(n = 33)
Median, months (95% CI)25.821.725.921.419.015.7
(22.8, 27.7)(17.7, 23.8)(20.0, 32.4)(12.3, 25.8)(13.6, 31.9)(12.8, 25.4)
Hazard ratio (95% CI)0.775 (0.614, 0.979)0.568 (0.388, 0.884)0.786 (0.484, 1.278)
P0.032a 0.010b 0.331b

Abbreviation: LDH, lactate dehydrogenase.