Table 2.

Association of mutational genotype with histopathologic findings

MNMBWWP
n 3110980
Median age, y (range)51 (19–75)48 (19–77)49.5 (18–73)n.s.
Gender, % female484548n.s.
Median Breslow, mm (range)1.40 (0.49–16.00)1.28 (0.22–11.00)0.93 (0.11–10.00)0.006
Breslow ≤ 1 mm, %9 (29.0)45 (41.7)45 (56.3)0.021
Clark level, %
 21 (3.2)12 (11.0)21 (26.3)
 315 (48.4)42 (38.5)38 (47.5)
 413 (41.9)55 (50.5)21 (26.3)
 52 (6.5)0 (0.0)0 (0.0)<0.001
Median mitotic figures/mm2 (range)1 (0–20)2 (0–18)1 (0–43)n.s.
Ulceration present, %3 (9.7)24 (22.4)8 (10.1)0.045

Abbreviation: n.s., not significant.