Table 1.

Patient characteristics

CharacteristicNo. of patients (n = 39 treated, 40 enrolled)
No. of cycles per patient, median (range)2 (1–23)
Age, median (range), y58 (31–85)
ECOG performance status
 09
 128
 22
Males/females21/18
Previous therapy
 Chemotherapy37
 Radiation therapy23
 Prior antiangiogenic therapy12
No. of prior chemotherapy regimens, median (range)5 (1–20)
Tumor types
 Colorectal cancers10
 Prostate cancer6
 Neuroendocrine carcinoma3
 Renal cell carcinoma (collecting duct and clear cell)2
 Adenoid cystic carcinoma; anorectal squamous carcinoma; chondroblastic osteosarcoma; endometrial; gastric cancer-signet ring; Kaposi's sarcoma; laryngeal cancer; lung adenocarcinoma; non–Hodgkin's lymphoma; ovarian cancer, endometrial type; pancreatic cancer; paratesticular rhabdomyosarcoma; signet ring adenocarcinoma (unknown primary); thymus carcinoma; thyroid-squamous cell carcinoma; tonsil-squamous cell carcinoma; transitional cell carcinoma; uterine leiomyosarcoma1 each