Table 1.

Characteristics of study populations, Consortium on genetic risk of metastatic and recurrent prostate cancer*

Metastatic prostate cancerRecurrence after radical prostatectomy
India-Cornell UWash UPLCOJHUFHCRCU PennMCC
Study design*Case-controlCase-controlNested case- controlNested case- controlCohortCohortCohort
Cases/controls (N)122/322295/45553/1168450/450NANANA
Cases/cohort (N)NANANANA92/42499/617137/371
Mean age at diagnosis (years)64.564.067.658.957.967.961.6
Nonwhite (%)100.039.5014.14.512.86.7
Pathologic Gleason score (%) in cases
<726.823.616.764.660.655.23.8
732.737.340.030.233.038.770.6
7+40.539.143.35.26.46.125.6
Stage (%) in cases
I0.00.00.00.072.628.02.9
II0.00.00.013.627.147.197.1
III0.00.00.051.70.225.00
IV100.0100.0100.00.00.00.00.0
  • *In metastatic cases (India-Cornell U, Wash U, PLCO), in recurrence cohorts (FHCRC, U Penn, HLMCC), and in the cases in the recurrence nested case-control study (JHU).

  • †Cases and controls matched on age at radical prostatectomy, race, and pathological stage and grade. Controls sampled using incidence density sampling.

  • ‡Study population was Asian Indian.

  • 39.5% was African Americans.