Table 2.

Univariate Cox regression analysis

VariableCharacteristicsRecurrence-free survival
HR95% CIPa
Zurich TMA
 Age at diagnosis1.0060.964–1.0500.772
 Gleason score (grouped)5–7 vs 8–102.9721.823–4.844<0.001
 Tumors stage (grouped)pT2a-c vs pT3a-42.3361.625–3.356<0.001
 Surgical margin statusNegative vs positive3.2682.069–5.161<0.001
 Preoperative PSA level< 10 ng/mL vs ≥ 10 ng/mL2.3171.432–3.7480.001
 Nuclear KPNA2 immunoreactivity0% vs > 0%2.0751.314–3.2770.002
 Nuclear NBS1 immunoreactivity0% vs >0%2.0130.732–5.5380.175
Regensburg TMA
 Age at diagnosis0.9780.942–1.0160.257
 Gleason score (grouped)5–7 vs 8–101.4000.816–2.4030.222
 Tumors stage (grouped)pT2a-c vs pT3a-42.0741.279–3.3620.003
 Surgical margin statusNegative vs positive0.1140.717–1.8070.582
 Preoperative PSA level<10 ng/mL vs ≥10 ng/mL1.3200.818–2.1320.255
 Nuclear KPNA2 immunoreactivity0% vs >0%1.7031.013–2.8640.044
  • aP < 0.05 are marked in bold.