Table 3.

Multivariate Cox regression analysis

VariableCharacteristicsRecurrence-free survival
HR95% CIPa
Zurich TMA
 Gleason score (grouped)5–7 vs 8–102.1191.250–3.5900.005
 Tumors stage (grouped)pT2a-c vs pT3a-pT42.01612.38–3.2840.005
 Surgical margin statusNegative vs positive2.5191.558–4.071<0.001
 Preoperative PSA level< 10 ng/mL vs ≥ 10 ng/mL1.9541.150–3.3210.013
 Nuclear KPNA2 immunoreactivity0% vs >0%2.1291.332–3.4030.002
Regensburg TMA
 Gleason score (grouped)5–7 vs 8–100.8510.425–1.7060.650
 Tumors stage (grouped)pT2a-c vs pT3a-pT41.9700.926–4.1920.078
 Surgical margin statusNegative vs positive0.8260.418–1.6330.583
 Preoperative PSA level<10 ng/mL vs ≥10 ng/mL1.6740.849–3.3040.137
 Nuclear KPNA2 immunoreactivity0% vs >0%2.6531.340–5.2530.005
  • aP < 0.05 are marked in bold.