Table 2.

Genotype frequencies, odds ratios and 95% CI comparing pathologic stage in RP patients

SNPsn (%)OR (95%CI)aPb
T1 or T2T3 or T4, or N1 or M1
−2835 C/A (rs2857654)
 CC622 (53.6)291 (52.4)Reference0.59
 AC458 (39.4)222 (40.0)1.02 (0.82–1.26)
 AA81 (7.0)42 (7.6)1.12 (0.75–1.67)
 Total1,161 (100.0)555 (100.0)
−2139 A/T (rs1024610)
 AA705 (61.5)320 (58.3)Reference0.28
 AT389 (33.9)203 (37.0)1.14 (0.91–1.42)
 TT53 (4.6)26 (4.7)1.06 (0.65–1.75)
 Total1,147 (100.0)549 (100.0)
−1811 A/G (rs3760399)
 AA1,080 (93.5)503 (90.8)Reference0.04
 AG+GG75 (6.5)51 (9.2)1.50 (1.03–2.18)
 Total1,155 (100.0)554 (100.0)
−927 G/C (rs3760396)
 GG729 (63.1)369 (66.6)Reference0.26
 CG380 (32.9)161 (29.1)0.82 (0.65–1.03)
 CC47 (4.0)24 (4.3)1.05 (0.62–1.79)
 Total1,156 (100.0)554 (100.0)
+764 C/G (rs2857657)
 CC696 (63.1)321 (60.7)Reference0.49
 CG358 (32.5)187 (35.3)1.12 (0.89–1.40)
 GG48 (4.4)21 (4.0)0.92 (0.54–1.58)
 Total1,102 (100.0)529 (100.0)
+3726 T/C (rs2530797)
 CC184 (16.1)78 (14.2)Reference0.61
 CT541 (47.5)271(49.5)1.14 (0.84–1.55)
 TT415 (36.4)199 (36.3)1.07 (0.78–1.48)
 Total1,140 (100.0)548 (100.0)
  • aAdjusted by the age at diagnosis.

  • bCochran–Armitage test for trend.