Table 3.

Frequency distributions of constructed haplotypes with D'Amico risk classifications

HaplotypesaAll subjectsLow riskIntermediate or high riskPbPc
H1AAAGCT0.2710.2750.2710.680.99
H2CAACCT0.1960.1850.2000.180.67
H3CTAGGC0.1890.1950.1900.640.98
H4CAAGCC0.1860.1880.1810.520.96
H5CAAGCT0.0890.1020.0830.01d0.04
H6CAGGCT0.0390.0320.0420.050.35
H7CAAGGC0.0120.0080.0150.030.18
Overall0.04
  • aThe SNPs order is the same as given in Figure 1.

  • bTwo-sided χ2 test, each haplotype compared with all other haplotypes.

  • cAfter 1,000 permutation test.

  • dOR for carriers versus noncarries, 0.80 (95% CI, 0.66–0.96).