Table 2.

Summary listing of all adverse events related to 17-DMAG

SystemAdverse eventGrade
12345
Blood/bone marrowLymphopenia21
Thrombocytopenia31
Raised neutrophils2
Raised leucocytes1
Low hematocrit1
Low red cell count1
Eosinophilia1
Low eosinophils1
CardiacHypotension1
Hypertension3
Sinus tachycardia1
ConstitutionalFatigue21
Alopecia2
Fever21
Weight loss1
GastrointestinalVomiting24
Nausea51
Diarrhea511
Dehydration11
Anorexia11
Heartburn1
Metabolic/laboratoryHepatic
AST411
ALT211
γGT1
ALP21
Raised bilirubin1
Nonhepatic
Hyponatremia31
Acidosis1
Creatinine1
Hypokalemia2
Hypergylcemia2
Raised amylase1
Raised CK1
Hyperuricemia1
Hypocalcemia1
High protein1
Low urea1
Ocular/ visualBlurred vision22
Dry eye12
Keratitis2
Eye (herpes simplex)1
Ocular surface disease2
PainJoint52
Headache1
Limb1
Myalgia2
Abdomen1
RenalRenal failure1
Proteinuria3
Oliguria1
OtherLimb edema2
Dry mouth3
Dizziness1
Depression1
Neuropathy1
Vivid dreams1
Nightmares1
Rash1
Voice change1
Muscle spasm1
Hand foot syndrome1