Table 1.

Patient characteristics

Patient IDTumor pathologyAgeGenderKPSOS (mo)HC typeDose (106)AdjuvantPrevaccination TxPostvaccination TxRelated adverse events
GBM1-1GBM39M9033.83*1ImiquimodTemozolomideTemozolomide, isoretinoin, celecoxib, reoperation, stereotactic radiosurgeryFatigue, nausea/vomiting, diarrhea
GBM1-2GBM39M90>88.87Mes1ImiquimodTemozolomideTemozolomide, isoretinoin, CCNU, GliadelFatigue, arthralgia, low-grade fever
GBM1-3GBM34M90>91.3Mes1ImiquimodTemozolomideTemozolomide, isoretinoinLymphadenopathy, injection site reaction, low-grade fever, myalgia
GBM1-4rec. GBM61M7018.57*1NoneTemozolomide, thalidomide, isoretinoin, Newcastle virus
GBM1-5GBM58M7010.3Pro1NoneTemozolomideIrinotecan, bevacizumab
GBM1-6GBM63F80>37.6Mes1ImiquimodTemozolomideTemozolomideShingles
GBM1-7rec. GBM41F8010.93Mes1NoneIrinotecan, bevacizumabIrinotecan, bevacizumab
GBM1-8rec. GBM34M100>40.5PN1Poly-ICLCErlotinib, temozolomide, ANG, CCNU, celecoxib, tamoxifen,CCNU, celecoxib, tamoxifen
GBM1-9GBM50M90>9.03*1Poly-ICLCTemozolomide
GBM5-1GBM40F8017.97*5NoneTemozolomide, isoretinoinCCNU, gef tinib, rapamycin, carboplatinInjection site reaction
GBM5-2rec. GBM54M8017.3*5NoneTemozolomide, isoretinoin, CCNUCarboplatinAllergic rhinitis, itching at injection site, pruritis
GBM5-3GBM26M9081.4PN5ImiquimodTemozolomide, isoretinoin, CCNUCarboplatin, irinotecan, bevacizumab, dasatanib, simvastatin, rosiglitazone, procarbazine, CCNU, cyclophosphamideInjection site itching, dryness and pruritus, lymphadenopathy, nausea, diarrhea, vomiting, fatigue
GBM5-4GBM43M90>59.0Mes5ImiquimodTemozolomideTemozolomide
GBM5-5GBM45F9034.97PN5NoneTemozolomideIrinotecan, bevacizumab, CCNU, erlotinib
GBM5-6rec. GBM53M8022.33Mes5Poly-ICLCTemozolomide, GliadelIrinotecan, bevacizumabNausea, heartburn, constipation
GBM10-1rec. GBM58F7028.93PN10NoneTemozolomide, irinotecan, paclitaxelHeadaches, nausea/vomiting
GBM10-2GBM70F10023.0*10NoneTemozolomidep-EGFR/p-ErbB2 inhib, everolimus, carboplatin, bevacizumab, CCNU
GBM10-3GBM50M9036.33*10ImiquimodTemozolomideIrinotecan, bevacizumabDermatitis, rash
GBM10-4GBM59M8052.6Pro10ImiquimodTemozolomide, isoretinoinIrinotecan, bevacizumab, carboplatin, CCNUAnorexia, abdominal pain
GBM10-5GBM64M9013.63Mes10NoneTemozolomideBevacizumab, CCNU
GBM10-6GBM66M9037.73Mes10ImiquimodTemozolomideIrinotecan, bevacizumab, CCNU, etoposide, procarbazine, tamoxifenFatigue, left shoulder pain/arthralgia
GBM10-7rec. GBM74F6017.07Mes10NoneTemozolomideTemozolomide
GBM10-8rec. GBM52M6016.23PN10NoneTemozolomideUpper lip blisters, rash

Abbreviation: Tx, treatment.