Table 1.

Clinicopathological findings

FeatureNumber of patients, n = 116%*
Gender
 Male8271
 Female3429
Age (y)
 Mean ± SD62.4 ± 9.9
 Median63
Tumor distance from anal verge (cm)
 0–65547
 >6–126052
 >12–1611
cT stage
 232
 310591
 487
cN stage
 Positive8573
 Negative3127
Neoadjuvant treatment regime
 50.4 Gy + Standard 5-FU7363
 50.4 Gy + Intensified 5-FU/Oxaliplatin4337
Surgical procedure (including TME)
 Low anterior resection8372
 Abdominoperineal resection3228
 Hartmann's procedure11
Resection status
 R0116100
 R100
 R200
Circumferential resection margin (CRM) <1 mm
 Negative116100
 Positive00
Tumor regression grading
 000
 11311
 22925
 36354
 4119
ypT stage
 01210
 187
 22522
 36354
 487
ypN stage
 07262
 13026
 21412
ypM stage
 010893
 187
Cancer recurrence
 No cancer recurrence9076
 Isolated local recurrence00
 Isolated distant recurrence2219
 Combined local + distant recurrence43