Table 1.

Associations of preoperative sB7-H1 levels (ng/mL) with clinical and pathologic features for 172 ccRCC patients

Featuren (%)Mean sB7-H1 (median; range)P
Age at surgery, y
 <6596 (56)0.32 (0.22; 0–3.00)0.308
 ≥6576 (44)0.36 (0.26; 0–4.40)
Gender
 Women45 (26)0.40 (0.24; 0–4.40)0.438
 Men127 (74)0.32 (0.22; 0–3.00)
Tumor size, cm
 <575 (44)0.28 (0.21; 0–2.25)0.063
 5 to <737 (22)0.32 (0.24; 0.02–3.00)
 7 to <1032 (19)0.49 (0.26; 0–4.40)
 ≥1028 (16)0.37 (0.29; 0–1.25)
2002 Primary Tumor Classification
 pT1a, pT1b102 (59)0.29 (0.22; 0–3.00)0.017
 pT217 (10)0.39 (0.21; 0–1.37)
 pT3a, pT3b, pT3c, pT453 (31)0.42 (0.29; 0–4.40)
Regional lymph node involvement
 pNX/pN0162 (94)0.34 (0.23; 0–4.40)
 pN1/pN210 (6)0.34 (0.32; 0.14–0.86)0.232
Distant metastases
 M0148 (86)0.34 (0.23; 0–4.40)0.076
 M124 (14)0.34 (0.30; 0.13–0.86)
2002 TNM Stage Groupings
 I100 (58)0.30 (0.22; 0–3.00)0.079
 II14 (8)0.39 (0.20; 0–1.37)
 III33 (19)0.47 (0.26; 0–4.40)
 IV25 (15)0.33 (0.29; 0.13–0.86)
Tumor thrombus
 None136 (79)0.31 (0.22; 0–3.00)0.086
 Level 021 (12)0.40 (0.32; 0–1.63)
 Level I–IV15 (9)0.55 (0.27; 0–4.40)
Nuclear grade0.044
 1, 272 (42)0.26 (0.20; 0–1.66)
 3, 4100 (58)0.40 (0.24; 0–4.40)
Coagulative tumor necrosis
 Absent126 (73)0.30 (0.22; 0–3.00)0.003
 Present46 (27)0.46 (0.30; 0–4.40)