Table 1.

Validation summary on potential survival marker genes

MarkersCopy number gains (losses) are associated to survival in 38 MPNSTs?Differential mRNA expression exists in arrays between tumorswith and without CNAs?CNAs identified by aCGH are confirmed by qRT-PCR in same MPNSTs?Differential mRNA expression is confirmed by qRT-PCR in same MPNSTs?Gene amplification in FISH is associated with survival of 87 MPNSTs?High protein expression in IHC is associated with survival of 87 MPNSTs?
SOX5SignificantNoSignificantNot significantn/aNot significant
NOL1SignificantYesSignificantSignificantn/an/a
MLF2SignificantYesSignificantSignificantn/an/a
FOXM1SignificantYesSignificantSignificantn/aSignificant
FKBP4SignificantYesSignificantSignificantn/an/a
CDK4SignificantYesSignificantSignificantSignificantn/a
TSPAN31SignificantYesSignificantNot significantn/an/a
ERBB1Not significantNon/an/aNot significantn/a
MYCNot significantYesn/an/aNot significantSignificant
TP53Not significantNon/an/an/aNot significant