Table 1.

Patient characteristics

VariableAll patientsElderly patients
(n = 93)>50 years (n = 22)
AgeMedian, range, y36 (13–83)62 (50–83)
Age>50 y22 (24%)22
SexMale40 (43%)8 (36%)
Histologic subtypeNS64 (69%)13 (59%)
NS 140 (43%)7 (32%)
NS 216 (17%)3 (14%)
Mixed cellularity4 (4%)2 (9%)
Lymphocyte rich4 (6%)2 (9%)
Lymphocyte depleted2 (2%)1 (5%)
Not classifiable19 (20%)4 (18%)
Immunohistochemical Staining
CD30 positive88/91 (98%)20/21 (95%)
CD15 positive88/91 (98%)21/21 (100%)
CD20 positive20/75 (27%)2/14 (14%)
StageLimited44 (48%)7 (37%)
Advanced48 (52%)14 (63%)
Presence of B-symptomsYes32 (35%)12 (55%)
Bulky diseaseYes32 (35%)4 (18%)
IPS0–268 (74%)11 (52%)
3–724 (26%)10 (48%)
TreatmentABVD55 (59%)11 (50%)
BEACOPP32 (34%)6 (25%)
MOPP/other6 (7%)6 (25%)