Table 3.

Associations between plasma EBV-DNA concentration and clinical characteristics in EBV-associated HL

EBV-DNA
VariableCopy number/mL (median, range)P*
Age
<50 y (n = 11)0 (0–5,760)0.006
>50 y (n = 7)11,200 (0–135,600)
Gender
Female (n = 7)3,600 (0–135,600)0.6
Male (n = 11)300 (0–40,000)
Stage
Limited (n = 12)73 (0–11,000)0.01
Advanced (n = 6)12,790 (0–135,600)
Presence of B-symptoms
No (n = 13)0 (0–11,000)0.001
Yes (n = 5)14,380 (5,760–135,600)
Bulky disease
No (n = 11)300 (0–135,600)0.6
Yes (n = 7)1,200 (0–11,000)
IPS
0–2 (n = 12)0 (0–11,200)0.007
3–7 (n = 6)10,070 (300–135,600)

*P values of Wilcoxon ranksum test are given for comparison of dichotomous characteristics.