Table 2.

Patient dosing and DLT assessment

TH-302 dose level, mg/m2Arm AArm B
Number of DLTsMedian (range), number of cyclesNumber of DLTsMedian (range), number of cycles
7.5–2400/142 (1–8)NA
4800/63 (1–4)NA
5751/122 (1–5)NA
6702/52 (2–3)0/142 (1–13+)
940NA2/62.5 (1–3)