Table 3

Non-dose limiting (grades 1 and 2) toxicities of fish oil ethyl ester soft gelatin capsulesa

Abnormal body smell
Dose, g/kg/dayNbAbnormal taste of foodAbnormal taste in mouthPatientOthersBelchingFlatulenceOtherDescription of other
0.1021Difficulty swallowing
0.1531212Incontinent of oil; cramping
0.2041
0.2571221222Nausea/vomiting
Nausea/vomiting
0.30735c1530
0.356111113Constipated, passage of orange stools;  diarrhea; constipation
0.40312Dry mouth; bloating
0.453111211Soft stools and vomiting
0.502111111
Total6106415911
  • a Shown are number of patients who experienced ω-3 fatty acid-specific toxicities less than grade 3 by the actual dose given.

  • b Total patients at dose level.

  • c Fishy for some patients.