Table 3

Urinary metabolites expressed as percentage of dose

Time (hr)Percentage of dose
UPMaTMATMZAIC
0–40.831.63.53.2
4–81.31.72.05.4
8–243.21.003.3
24–336b12000
Total172.35.512
  • a UPM, early eluting unidentified polar metabolite(s)/degradation product(s).

  • b All drug-related radioactivity in urine after 24 hr was assumed to be associated with UPM.