Table 1

Effect of Taxol on proliferation of human breast cancer cells

Cell lineIC50am)
HER-2/neu-overexpressing cells
 MDA-MB4538
 BT-4833
 SKBr-310
 MDA-MB3615
 BT-47410
Cells with basel levels of HER-2/neu
 MDA-MB4350.001
 MDA-MB2310.001
 HBL-1000.008
 MCF-70.010
  • a Taxol concentrations required to inhibit 50% of cell growth.