Table 5

K-ras mutational spectrum in brush cytology specimens and corresponding carcinomas of 60 of the 71 patients with a precise etiology of the malignant stenosis based on histology of the stenotic lesion

Mutations in carcinomasaMutations in brush cytologyaTotal
CysSerArgValAspAlaGlyb
Cys112
Ser
Arg213
Val8311
Asp15217
Ala11
Glyb2626
Total1281513360
  • a The six possible mutations code for cysteine, serine, arginine, valine, aspartic acid, and alanine.

  • b Wild-type codon 12 (GGT) codes for glycine.