Table 1

Summary of patients and characteristics of CALGB studies 9181 and 9182

Protocol
Variable91819182
No. of patients143239
No. of evaluable patients133233
Treatment studiedDose of MAMitoxantrone added to hydrocortisone
P for therapeutic effect0.680.87
Performance status (% of patients)
 04839
 14345
 2815
Median initial hemoglobin (g/dl)12.312.2
Median initial weight (kg)81.983.7
Median survival (days)376369
No. dead at time of analysis (%)131 (98.5)200 (85.8)
Median no. of PSAs (range)6 (1–39)6 (1–30)