Table 2

Validation of rva of PSAa

CALGB study
Parameter91819182
Coefficientb24.4815.54
SE7.324.0
P 0.00080.0001
No. of patients137233
No. of deaths125188
Model LRc28.771
• a Both models also included the level of PSA as the natural log (PSA), and the coefficients for this variable were 0.221 and 0.274, respectively; that is, the level of log (PSA) was given greater weight in the results for protocol 9182.

• b The coefficient is b2 of Eq. C ; the SEs refer to the expected variance in the estimates of the coefficients; and the Ps indicate the significance of the associations between rva and survival time in these three groups of patients.

• c LR, overall likelihood ratio.