Table 1

Characteristics of 775 AML patients, by availability of ERM data and specimen type

Patients with ERM dataPatients without ERM dataa(n = 514)
All with ERM data (n = 261)Specimen type
Blood(n = 152)Marrow (n = 103)
Age (yr)
 Median43444146
 Range17 –6917 –6418 –6915 –72
Sex
 Male150 (57%)86 (57%)59 (57%)277 (54%)
 Female111 (43%)66 (43%)44 (43%)237 (46%)
Race
 White219 (84%)127 (84%)86 (83%)439 (85%)
 Black28 (11%)17 (11%)11 (11%)51 (10%)
 Other14 (5%)8 (5%)6 (6%)24 (5%)
Histology (FAB)
 M158 (22%)36 (24%)22 (21%)97 (19%)
 M299 (38%)54 (36%)43 (42%)196 (38%)
 M317 (7%)5 (3%)12 (12%)72 (14%)
 M443 (16%)25 (16%)14 (14%)54 (11%)
 M534 (13%)24 (16%)10 (10%)38 (7%)
 M61 (<1%)1 (1%)020 (4%)
 M71 (<1%)1 (1%)07 (1%)
 M03 (1%)3 (2%)013 (3%)
 Other5 (2%)3 (2%)2 (2%)17 (3%)
WBC (1000/μl)
 Median48.661.330.79.3
 Range0.8 –4163.0 –4160.8 –2680.4 –370
Peripheral blasts (%)
 Median61684527
 Range0 –990 –990 –980 –99
Peripheral blasts (1000/μl)
 Median20.026.59.22.0
 Range0.0 –3780.0 –3780.0 –2500.0 –314
Hemoglobin (gm/dl)
 Median9.49.69.19.2
 Range5.1 –15.05.1 –15.05.6 –14.34.1 –15.4
Platelets (1000/μl)
 Median52505454
 Range3.0 –7007.0 –7003.0 –3332.0 –347
Induction Ara-C dose
 200 mg/m2182 (70%)109 (72%)69 (67%)347 (68%)
 2.0 gm/m262 (24%)33 (22%)28 (27%)119 (23%)
 3.0 gm/m217 (7%)10 (7%)6 (6%)48 (9%)
ERM (%)
 Median24.718.836.1
 Range0.3 –99.10.3 –99.11.2 –97.2
 <15%101 (39%)71 (47%)28 (27%)
 ≥15%160 (61%)81 (53%)75 (73%)
  • a Includes 507 patients from S8600 without leukemic blasts available for study and 7 patients with degraded DNA.