Table 1

Comparison of deduced amino acid residues of human and rabbit carboxylesterases at the four positions for which the reported sequences of the human enzymes differ

Tissue of originAligned amino acid residuesa
#18#57#363#538
Human (99% overall identity)
 Macrophage (I57004)bAlanineGlutamineAlanine
 Liver (1) (A48809)bAlanineGlycineGlutamineGlycine
 Liver (2) (I61085)bGlycineGlycineGlycine
Rabbit (81% identical to human)
 LiverAlanineAlanine
Human (enzyme sequence used in this study)
 LiverAlanineAlanine
  • a Amino acid sequences of all five carboxylesterases were aligned and numbered using the reported sequence for liver (1) carboxylesterase.

  • b PIR accession number.