Table 1

Centrosome abnormalities in patients with pancreatic carcinoma, adenoma, endocrine tumor, or chronic pancreatitis

Case no.DiagnosisAgeSexStagingaDifferentiationCentrosome abnormalityb
1 Tubular adenocarcinoma59MT2N1M0Well+
2 Tubular adenocarcinoma68MT3N1M0Well+
3 Tubular adenocarcinoma73MT2N0M0Well+
4 Tubular adenocarcinoma68MT3N1M0Well+
5 Tubular adenocarcinoma69FT2N1M0Well
6 Tubular adenocarcinoma40MT3N1M0Moderate+
7 Tubular adenocarcinoma69MT3N0M0Moderate+
8 Tubular adenocarcinoma50FT3N1M0Moderate
9 Tubular adenocarcinoma59MT3N1M0Poor+
10 Tubular adenocarcinoma56FT2N1M0Poor+
11 Tubular adenocarcinoma74FT2N0M0Poor+
12 Tubular adenocarcinoma47MT3N1M1Poor+
13 Mucinous cystadenocarcinoma55FT3N1M0+
14 Intraductal papillary adenomac46F+
15 Mucinous cystadenomac75F+
16 Serous cystadenoma49M
Endocrine tumors
17 Endocrine tumor (malignant)26MWell
18 Endocrine tumor (malignant)51MWell
19 Endocrine tumor (malignant)54FWell
20 Chronic pancreatitis46M
21 Chronic pancreatitis46M
22 Chronic pancreatitis69M
23 Chronic pancreatitis69M
24 Chronic pancreatitis54M
  • a Tumor stage was assessed according to Union International Contre Cancer-Tumor-Node-Metastasis staging.

  • b Centrosomes were considered abnormal if they measured >2 μm in diameter and/or if they were present in three or more per cell.

  • c Tumor cells showed moderate to severe atypia.