Table 4

Concordance for retention or LOH

Cell lineCulture time (months)aRetention of heterozygositybLOH tumor/Cell lineConcordancecLoss of the same alleled
HCC95692/210/1212/14 (86%)10/10 (100%)
HCC4615713/135/1118/24 (75%)5/5 (100%)
HCC11714215/158/1023/25 (92%)8/8 (100%)
HCC11954211/118/819/19 (100%)8/8 (100%)
HCC1313403/318/2221/25 (84%)18/18 (100%)
HCC13594015/155/1320/28 (71%)5/5 (100%)
HCC14383813/138/1021/23 (91%)8/8 (100%)
HCC1588362/215/1817/20 (85%)15/15 (100%)
HCC18333110/1011/1121/21 (100%)11/11 (100%)
HCC21082512/1213/1325/25 (100%)13/13 (100%)
HCC22792114/145/819/22 (86%)5/5 (100%)
HCC24501214/149/923/23 (100%)9/9 (100%)
Total124/124 (100%)115/145 (79%)239/269 (89%)115/115 (100%)
  • a Ranked by cell line time period of culture.

  • b Number of informative loci with retention of heterozygosity in both tumors and cell lines.

  • c Concordance for both retention and LOH.

  • d For comparisons when both tumor and cell line demonstrated LOH for an individual marker.