Table 2

Characteristics of squamous cell lung carcinomas subdivided according to PCNA index and vessel density

Group AGroup BGroup CGroup D
PCNA index (%)37.7 ± 10.442.1 ± 12.610.3 ± 6.411.0 ± 5.6
Vessel density2.7 ± 1.518.3 ± 12.73.4 ± 1.915.6 ± 8.5
Apoptosis0.31 ± 0.210.47 ± 0.350.28 ± 0.260.40 ± 0.34
Pa0.070.140.27
VEGF
 Positive19 (95%)21 (95%)5 (18%)6 (33%)
 Negative112212
P0.94<0.0001<0.0001
bFGF
 Positive8 (44%)15 (71%)19 (76%)12 (75%)
 Negative10664
P0.080.030.07
PDGF
 Positive14 (70%)10 (55%)10 (45%)8 (47%)
 Negative68129
P0.350.100.15
Growth in mice
 Yes8 (53%)4 (27%)12 (60%)3 (27%)
 No71188
P0.130.690.18
Metastasisb
 Positive14 (74%)15 (68%)14 (52%)12 (66%)
 Negative57136
P0.690.130.64
Survival (weeks)2888111117
P0.130.030.009
  • a All Ps were calculated vs. group A.

  • b One case could not be defined.