Table 3

Characteristics of the tumors according to high (groups B and D) or low (groups A and C) vessel density

Groups B and DGroups A and CP
Vessel density17.1 ± 11.03.1 ± 1.7<0.0001
PCNA index (%)28.1 ± 18.521.9 ± 16.00.07
Apoptosis0.44 ± 0.340.29 ± 0.240.01
VEGF
 Positive27 (67%)24 (51%)0.12
 Negative1323
bFGF
 Positive27 (73%)27 (63%)0.33
 Negative1016
PDGF
 Positive18 (51%)24 (57%)0.61
 Negative1718
Growth in mice
 Yesf7 (27%)20 (57%)0.01
 No1915
Metastasisa
 Positive27 (67%)28 (61%)0.52
 Negative1318
Survival (weeks)111640.20
  • a One case could not be defined.