Table 6

Serum cytokine levels, tumor load, and pathological characteristics of patients with head and neck squamous cell carcinoma

CytokinesaTumor size (ml)Pathology
PatientIL-6IL-8VEGFTNMPrimaryMetastasisDifferentiationbInflammatoryc cells
12.729.5779.7T4N1M016.81.9NA++
228.524.4900.6T4N0M095.40.00+++
37.527.6430.1T3N2M0NANA+++
47.2130.91084.4T4N0M092.40.0+++
553.540.9699.1T4N1M023.20.0+++
668.1194.5380.9T3N3M1NANA++++
7129.60.0146.8T4N3M022.282.60++
82.00.0362.9T4N1M039.70.0+++++
94.83.31073.3T4N2cM044.343.7+++++
100.523.6374.2T2N1M014.81.6+++
111.963.6234.9T4N3M024.3123.3+NA
  • a Cytokines were detected in patients’ serum and presented as pg/ml.

  • b Differentiation was classified as well differentiated, +++; moderately differentiated, ++; poorly differentiated, +; and undifferentiated, 0.

  • c The inflammatory infiltrate cells were evaluated as: intense, +++; moderate, ++; mild, +; or absent. NA, not applicable.