Table 1

Patient characteristics

Patients treated with 2-CdAPatients treated with 2′-DCF
Gender
 Male35 (90%)23 (85%)
 Female4 (10%)4 (15%)
Age (yrs) Mean (range)48 (34–85)58 (35–74)
No. of purine analogue cycles
 Mean (range)113 (5–25)
Disease duration before therapy (mo) Mean (range)12 (1–199)3.6 (0.033–39.7)
Prior therapy
 None1825
 Splenectomy50
 IFN112
 Splenectomy, IFN30
 Splenectomy, IFN, 2′-DCF20
% bone marrow HCsa pretherapy Mean (range)69 (10–95)77 (5.98)
WBC (×109/liter) Mean (range)3.4 (0.6–22.2)2.9 (0.2–8.3)
Platelets (×109/liter) Mean (range)76 (11–466)92 (29–302)
ANC (×109/liter)b Mean (range)1.05 (0.092–4.712)0.8 (0–2.1)
  • a HC, hairy cell.

  • b ANC, absolute neutrophil count.