Table 2

Proliferative responses of PBMCs to KLH and MUC1 in immunized chimpanzeesa

Week of immunization
02482527
Identification no.AgNo AgAgSINo AgAgSINo AgAgSINo AgAgSINo AgAgSINo AgAgSI
575KLH1.21.41.21.72.51.50.32.58.0b3.218.85.9b4.411.72.6b14.139.52.8b
MUC11.21.61.41.71.10.70.32.27.1b3.23.61.14.43.40.814.127.11.9
638KLH0.60.10.26.211.71.90.41.23.2b1.17.16.3b9.725.32.6b12.597.47.8b
MUC10.61.01.76.29.51.50.42.76.9b1.19.78.7b9.79.61.012.521.51.7
654KLH3.05.41.82.03.11.51.420.814.9b1.711.66.8b4.516.33.6b0.516.032.8b
MUC13.01.20.42.00.90.41.42.21.51.72.81.64.54.00.90.52.65.2b
664KLH2.07.53.8b1.420.414.3b4.316.94.0b1.716.510.0b13.221.91.71.14.54.1b
MUC12.00.80.41.42.21.54.31.80.41.74.12.5b13.232.72.5b1.10.90.8
  • a PBMCs were cultured with 100 μg/ml KLH, MUC1 peptide, or no antigen for 3–7 days and proliferation measured by incorporation of [3H]thymidine. Data are expressed as absolute cpm (× 10−3), and SIs are expressed as fold increase in proliferation in the presence of antigen. Ag, antigen.

  • b SI ≥ 2.5.