Table 3

CMYC amplificationa

TumorAmplification (%)Cases studiedMethodReference
Bladder387FISHSauter et al. (44)
333FISH/ArraySchraml et al.
Breast1100SouthernOttestad et al. (45)
4100SouthernLizard-Nacol et al. (46)
654SouthernContegiacomo et al. (47)
6154SouthernWatson et al. (48)
8311SouthernBorg et al. (49)
1274FISH/ArraySchraml et al.
171052SouthernBerns et al. (50)
18101DotBlotChen et al. (51)
2152SouthernTavassoli et al. (52)
2565SouthernRoux-Dosseto et al. (53)
4148SouthernBonilla et al. (5)
Carcinoidb02FISH/ArraySchraml et al.
Colon329FISH/ArraySchraml et al.
423PCRRochlitz et al.(54)
3222SlotBlotWang et al. (55)
DCISb15FISH/ArraySchraml et al.
Endometrium1811FISH/ArraySchraml et al.
6615SouthernBorst et al. (56)
Head/Neck021SouthernSomers et al. (57)
617FISH/ArraySchraml et al.
966SouthernLeonard et al. (58)
1021SouthernMerritt et al. (59)
1540SouthernVolling et al. (60)
258SouthernHaughey et al. (61)
Kidney522FISH/ArraySchraml et al.
836DotBlotKozma et al. (62)
Lung023SouthernSekine et al. (63)
247 (SCLC)DotBlotNoguchi et al. (64)
978FISH/ArraySchraml et al.
1145 (SCLC)SouthernWong et al. (12)
336 cell linesSouthernSaksela et al. 1(10)
Melanomab03FISH/ArraySchraml et al.
Ovary824FISH/ArraySchraml et al.
2825SouthernBerns et al. (65)
5012SouthernSasano et al. (66)
Pheochromocytoma02FISH/ArraySchraml et al.
06SouthernLiu et al. (67)
Phylloidesb04FISH/ArraySchraml et al.
Prostate015SouthernFournieret al. (16)
021SouthernLatil et al. (18)
019FISH/ArraySchraml et al.
825FISHJenkins et al. (68)
Stomach010FISH/ArraySchraml et al.
450SouthernRanzani et al. (69)
714SouthernKoda et al. (7)
1351DotBlotNakata et al. (70)
1811SouthernNakasato et al. (8)
2623SouthernHajdu et al. (71)
Testis021SouthernSchmidt et al. (72)
617FISH/ArraySchraml et al.
Thyroid02FISH/ArraySchraml et al.
045SouthernTerrier et al. (73)
715SouthernYang et al. (74)
  • a Studies on metastatic samples or tumors from treated patients were excluded.

  • b No data in the literature were found for phylloides tumors, carcinoids, melanoma, or DCIS.