Table 1

Clinicopathological parameters according to cyclin D1 mRNA expression and ER status in stage I-II breast cancer

Overall (n = 253)ER-positive group (n = 182)ER-negative group (n = 71)
Cyclin D1Cyclin D1Cyclin D1
LowHighLowHighLowHigh
Features(n = 126)(n = 127)P(n = 74)(n = 108)P(n = 52)(n = 19)P
Age (yrs)
 <50564330332610
 50–7055643558206
 >7015200.2419170.427630.820
Menopausal status
 Not known322210
 Premenopausal49432734229
 Postmenopausal74820.43145720.45429100.792
Tumor size (cm)
 Not known613130
 <1825131
 1–248483345153
 >264760.10633610.05531150.438
Tumor type
 Not known843351
 Ductal797349613012
 Lobular040400
 Others39460.09522400.1271761.000
Tumor grade
 Not known733340
 156433739194
 2526629542312
 311150.1445120.132630.354
Vascular invasion
 Not known2032112795
 Negative59413433258
 Possible131591540
 Positive34390.20820330.2881460.444
Lymph node status
 Not known151691363
 Negative1921162031
 ≤3 positive nodes3133253261
 >3 positive nodes61570.86224430.57537140.756
ER status
 Negative5219
 Positive741080.0001a
  • a Statistically significant.