Table 1

Effects of p53 and p21WAF1 gene transduction on SUIT-2 and AsPC-1 cellsa

3 days after treatment
Cell linePretreatmentPBSAd-lacZAd-p21Ad-p53VP-16
SUIT-2Cell no. (×104)8.4 ± 0.249.9 ± 0.737.9 ± 1.214.6 ± 0.57.3 ± 0.47.6 ± 0.9
Dead cells (%)2.4 ± 1.01.2 ± 0.11.3 ± 0.12.2 ± 0.56.6 ± 0.27.1 ± 1.1
Telomerase activity (%)100 ± 2105 ± 3112 ± 1100 ± 422 ± 7108 ± 0
AsPC-1Cell no. (×104)8.3 ± 0.234.8 ± 1.030.0 ± 0.712.1 ± 1.110.8 ± 1.26.1 ± 0.9
Dead cells (%)0.7 ± 0.91.8 ± 0.41.9 ± 0.93.6 ± 1.412.2 ± 0.810.5 ± 2.4
Telomerase activity (%)100 ± 1104 ± 2100 ± 397 ± 414 ± 2105 ± 1
  • a Values represent mean ± SD of three independent wells.