Table 2

Cell cycle phase distribution of HT29 cells after TAX chronic exposure

Cells were treated with various TAX concentrations and subjected to flow cytometric analysis after treatment as described in “Materials and Methods.” Culture medium with TAX was changed after 48 h.
Treatment%Time (h)
24487296120
G155a66756672
ControlS4122183022
G2/M412746
G15366756771
0.5 nmS4221192721
G2/M513668
G14864626570
1 nmS4423252824
G2/M8131376
G14463636370
5 nmS4022242720
G2/M1615131010
G14863697371
10 nmS3622162121
G2/M16151568
G15234Fb52F
50 nmS3352F34F
G2/M1514151415
G1111FFF
100 nmS419FFF
G2/M9570889080
  • a Data represent mean values from three separate experiments; SD, <5%.

  • b F, cells or nuclei detected as damaged.