Table 3

Relationship between p53 mutations and clinicopathological variables in ovarian cancer

p53 mutation
VariableNone(n = 36)Missense(n = 62)Null(n = 32)P
Age (yrs)57.3 (31–84)a59.3 (37–89)a60.0 (44–82)aNSb
Histology
 Serous2240260.16
 Other14226
Stage
 I/II15102<0.001
 III/IV215230
Grade
 I1040<0.001
 II/III265832
Ascites
 Yes2446300.02
 No12162
Cytoreduction
 Optimal2541160.20
 Suboptimal112116
Lymph nodes
 Positive2990.003
 Negative15153
 Not done193820
  • a Age range.

  • b NS, not significant.