Table 3

%Tissue GSH levels in nmol/mg at baseline and 3 months and plasma oltipraz levels in ng/ml at 3 months, by dose

DoseBaseline3-monthChange% changePlasma oltipraz
20 mg/day1117655%0.0
20 mg/day105−5−50%4.6
20 mg/day111219%8.2
50 mg/day85−3−38%8.3
100 mg/day50.4−4.6−92%57.0
100 mg/day82921263%28.0
125 mg 2×/wka484100%129.0
125 mg 2×/wk92−7−78%264.0
125 mg 2×/wk58360%Missing
  • a 2×/wk, two times per week.