Table 4

%Tissue GST levels in nmol/min/mg at baseline and 3 months, and plasma oltipraz levels in ng/ml at 3 months, by dose

DoseBaseline3-monthChange% changePlasma oltipraz
20 mg/day2082282010%0.0
20 mg/day14614600%4.6
20 mg/day213193−20−9%8.2
50 mg/day256269135%8.3
100 mg/day16037−123−77%57.0
100 mg/day5443−11−20%98.0
100 mg/day23219196852%28.0
125 mg 2×/wka12079−41−34%129.0
125 mg 2×/wk175164−11−6%264.0
125 mg 2×/wk10310855%Missing
  • a 2×/wk, two times per week.