Table 1

%p73 allelic expression in 24 informative ovarian cancers and normal tissuesa

Case no.Cancer stageHistologyNormal tissuesExpressed alleles (normal tissues)Expressed alleles (cancer tissues)
1IVClearbCervixGC/ATGC/AT
5IcSerousLymphocyteGC/ATGC/AT
8IIcSerousLymphoctyeGC/ATGC/AT
13IIIcMuciLymphocyteGCGC/AT
14ISerousCervixGC/ATGC/AT
17IVSerousEndocGC/ATGC/AT
20IIIcMuciEndoGC/ATGC/AT
21IIIbMuciLymphocyteGCGC
30IIcSerousLymphocyteGC/ATGC/AT
33IIIcSerousLymphocyteGC/ATGC/AT
36IIcSerousEndoGCGC
38BorderdMuciEndoGC/ATGC/AT
41IIIcSerousEndoGC/ATGC/AT
42IIIcMuciEndoGC/ATGC/AT
45IIbEndocaEndoGC/ATGC/AT
46IIbEndocaEndoATGC/AT
47IcEndocaCervixGC/ATGC/AT
48Ia1MuciOvaryGC/ATGC/AT
51IIIcSerousLymphocyteGCGC/AT
54IIaClearCervixGC/ATGC/AT
58IIIEndocaLymphocyteGC/ATGC/AT
60IIClearLymphocyteGC/ATGC/AT
24 LOHIIIcSerousLymphocyteGC/ATGC/AT
61 LOHIIMuciLymphocyteGC/ATGC/AT
  • a Allelic expression in the GC/AT polymorphism site. Samples 13, 46, and 51 showed allelic imbalanced expression with biallelic expression in tumor and monoallelic expression in normal tissues; samples 21 and 36 showed monoallelic expression in both tumor and normal tissues. T24 and T61 showed LOH and biallelic expressed in both tumor and normal tissues.

  • b Clear, clear cell carcinoma; serous, serous adenocarcinoma; muci, mucinous adenocarcinoma; endoca, endometroid carcinoma.

  • c Endo, endometrium.

  • d Border, borderline tumor.