Table 2

%p53 gene mutations in synchronous multiple lung cancers

Patient no.TumorExonCodonMutation
2Tumor 1Intron 4 to exon 524-bp deletion
Tumor 2No mutation
3Tumor 1Exon 7249AGG→TGG(Arg→Trp)
Tumor 2Exon 7249AGG→TGG(Arg→Trp)
5Tumor 1Exon 5155ACC→ATC(Thr→Ile)
Tumor 2Exon 5155ACC→ATC(Thr→Ile)
9Tumor 1Exon 5169ATG→AATG
Tumor 2Exon 5169ATG→AATG
Tumor 3Exon 5169ATG→AATG
10Tumor 1No mutation
Tumor 2Exon 5172GTT→TTT(Val→Phe)
14Tumor 1Exon 7246ATG→GTG(Met→Val)
Tumor 2Exon 7246ATG→GTG(Met→Val)