Table 1

%Studies excluded from the present meta-analysis

AuthorReasons for exclusionp53 effect on survival
Mitsudomi et al. (27)Only cell lines were studiedNSa
Passlick et al. (28)Observation <3 yearsNS, p53+ > p53− in stages I, II
Casson et al. (29)Survival rate not shownNS
Passlick et al. (30)Observation <3 yearsNS
Kashii et al. (31)Included in the study, old and young onlyNS
Fong et al. (32)Survival rate not shownNS
Fontanini et al. (33)Updated by Passlick et al. (30)NS
Harpole et al. (34)Updated by Begg and Mazumdar (6)p53− > p53+
Murakami et al. (35)Patients treated either surgery/chemo/radiationp53− > p53+ in advanced stage patients
Kwa et al. (36)Survival rate not shownNS
Pastorino et al. (37)Only hazard ratio givenNS
Costa et al. (38)Only hazard ratio givenNS
Komiya et al. (39)Survival rate not shownp53− > p53+ in squamous cell cancer
Yu et al. (40)Survival rate not shownp53− > p53+ in adenocarcinoma
Higashiyama et al. (41)Survival rate not shownNS
Kawasaki et al. (42)Treated with surgery and/or chemotherapyNS
de Anta et al. (21)Analyzed by mutation typeWild type > miss > null
MacKinnon et al. (43)Survival rate not shownNS
Lucchi et al. (44)Survival rate not shownNS
Huang et al. (45)Exon-by-exon analysis, patients overlapped with X7 and X8 mutations Huang et al. (22)Poor
Hayakawa et al. (46)Treated with radiationNS
Przygodzki et al. (47)Survival rate not shownNS
  • a NS, not significant.