Table 2

The levels of PGs in human gastric cancers

PG levelsa (ng/mg protein)PGE2TXB26-k-PGF
NCNCNC
Total (n = 42)166 ± 63198 ±b8354 ± 2359 ± 2661 ± 2571 ± 24
Histological typec
Intestinal (n = 17)152 ± 70210 ± 10449 ± 2361 ± 2357 ± 2971 ± 25
Diffuse (n = 25)175 ± 58190 ± 6557 ± 2257 ± 2864 ± 2270 ± 24
Depth of invasiond
T1, T2 (n = 24)170 ± 73211 ± 9650 ± 2355 ± 2661 ± 2769 ± 28
T3, T4 (n = 18)160 ± 48180 ± 5958 ± 2363 ± 2662 ± 2272 ± 19
Lymph node involvement
Negative (n = 13)176 ± 79215 ± 6757 ± 2863 ± 2766 ± 2975 ± 25
Positive (n = 29)161 ± 56190 ± 8852 ± 2057 ± 2559 ± 2369 ± 25
COX-2 overexpressione
Positive (n = 31)161 ± 57201 ±b9055 ± 2060 ± 2662 ± 2171 ± 26
Negative (n = 11)179 ± 80189 ± 5850 ± 3154 ± 2459 ± 3468 ± 20
  • a Mean ± SD; N, normal gastric mucosa; C, cancer tissue.

  • b P < 0.05, according to Welch’s t test.

  • c According to Lauren’s classification.

  • d According to the Tumor-Node-Metastasis classification.

  • e Positive, COX-2 C:N > 1.0; Negative, COX-2 C:N < 1.0.