Table 3

%Drug-related, nonhematological toxicities: worst toxicity per patient and dose level

Dose level (g/m2)No. of patientsCTC gradeDiarrheaMucositis/StomatitisAcidosisSkinVomitingPainFever/ Infection
20.04II111
III
IV
26.03II
III
IV
32.53II1
III1
IV1a
39.03II
III
IV
47.03II2211
III
IV
56.06II123232
III111
IV211
  • a Patient 10 (Hodgkin’s disease) died 19 days after autologous PBSCT because of fungal sepsis despite hematological recovery.