Variable | Categories | n | Unadjusted HR^{a} | 95% CI^{b} | P^{c} | Adjusted HR^{d} | 95% CI | P^{c} |
---|---|---|---|---|---|---|---|---|
Age at primary operation^{e} | 195 | 1.05 | 1.0–1.1 | 0.002 | 1.04 | 1.0–1.1 | 0.007 | |
FIGO stage | I/II | 159 | 1 | <0.0001 | 1 | <0.0001 | ||
III/IV | 36 | 9.7 | 5.2–17.9 | 7.8 | 4.0–15.2 | |||
Ki-67 expression^{f} | ≤35% | 149 | 1 | <0.0001 | 1 | 0.01 | ||
>35% | 46 | 4.2 | 2.3–7.8 | 2.6 | 1.3–5.3 | |||
MVD_{mean}^{g} | ≤90 | 149 | 1 | 0.0002 | 1 | 0.03 | ||
>90 | 46 | 3.0 | 1.6–5.6 | 2.1 | 1.1–4.1 | |||
Nuclear p16 expression | Index < 4 | 24 | 6.6 | 3.5–12.5 | <0.0001 | 2.9 | 1.3–6.5 | 0.01 |
Index ≥ 4 | 171 | 1 | 1 |
^{a} Analyses based on patients with complete information for all variables (n = 195).
^{b} CI, confidence interval.
^{c} Likelihood ratio test.
^{d} Hazard ratio adjusted for variables with P < 0.10 in the Cox PH regression model.
^{e} Continuous variable with hazard ratio given per year.
^{f} Proportion of positive nuclei.
^{g} MVD_{mean} in counts/mm^{2}.