Table 1

Concentrations of VEGF and coagulation factors

Concentration of VEGF and coagulation factors in tumor aspirates compared with normal plasma concentrations.

Normal plasma Median (range)Aspirated Tumor Fluid (n = 12) Median (range)Fold higher
Total protein (g/liter)60–8052 (33–74)
VEGF (ng/ml)0.04a18 (0.3–345)450×
Tissue factor (pg/ml)349 (296–469)b723 (400–4998)
TAT complex (μg/liter)2 (2–3.5)b126 (33–184)63×
Thrombomodulin (μg/liter)44 (35–55)c181 (39–700)
  • a Values are the medians (range) of normal plasma as reported in Ref. 13 .

  • b Values are the medians (range) of normal plasma as reported in Ref. 9 .

  • c Values are the medians (range) of normal plasma as reported in Ref. 18 and tumor aspirates.